Road Rovers follows the adventures of a group of anthropomorphic dogs (cano-sapiens, if you please) who came together to fight evil masterminds, as dogs often do.

The doggy gang came into being when The Master, a slightly sinister yet benevolent scientist who invented the Transdogmafier, a high-tech machine that could transform man's best friend into a cano-sapiens with super powers. The Master (aka Professor Shepherd) fell victim to the villainous General Parvo  and was forced to hand over his Transdogmafier, which Parvo used to create an army of mean dog mutants to serve his evil schemes. Prof. Shepherd decided to fight dog with dog and assembled his own team of super dogs.

The good dog gang included Exile, the Siberian Husky; Blitz, a German Dobberman; Colleen, an English Collie; and Shag the Swiss sheepdog. Top dog of the group was Hunter, an American Golden Retriever, who brought along his dog pound cellmate, Muzzle the Rottweiler. Muzzle was a bit crazy and dangerous so he was always gagged and restrained until the time came to unleash his bad self on the enemy.

All the dogs went through the Transdogmafier except for Muzzle (who really didn't need to be enhanced) and gained super powers like speed, martial arts expertise, laser vision and super strength. Named the Road Rovers, the transformed dogs battled General Parvo and other villains to make the world a safer place for man and animals alike. When a mission was completed, the Road Rovers returned to their normal canine form and returned to their country of origin.

Most of the show's humor came from pop culture references, canine puns and Hollywood in-jokes but the series went to the dogs after only 13 episodes.  Woof.